• Effect of oral gabapentin clonidine and hemodynamic responses during laryngoscopy and intubation Tracheal surgery in patients undergoing cholecystectomy

    Author(s):
    Mohammad Asadiseyedmahaleh
    Editor(s):
    Abbas Jedariforoughi (see profile)
    Date:
    2022
    Group(s):
    Public Health
    Subject(s):
    Medicine
    Item Type:
    Article
    Tag(s):
    medical science
    Permanent URL:
    https://doi.org/10.17613/8t7t-q135
    Abstract:
    Introduction: During general anesthesia, airway control is usually by laryngoscopy and endotracheal intubation, which results in mechanical stimulation. Laryngoscopy and endotracheal intubation are almost always associated with increased blood pressure and increased heart rate. Increased blood pressure and heart rate due to laryngoscopy and intubation may lead to myocardial ischemia, cerebral hemorrhage, and death in susceptible patients. Various drug agents have been used to prevent these responses, including adrenergic blockers, vasodilators, calcium channel blockers, and lidocaine. Clonidine is a α2-adrenoceptor agonist that has analgesic, anti-anxiety, anti-chills, and anti-inflammatory effects. Gabapentin is a gamma aminobutyric acid analogue that is primarily used to treat seizures, neuropathic pain, and hot flashes. The action of gabapentin in attenuating the response to laryngoscopy and intubation-induced hypertension is unknown.
    Metadata:
    Published as:
    Journal article    
    Status:
    Published
    Last Updated:
    1 year ago
    License:
    All Rights Reserved

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